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. 2014 Jul 10;111(6):1188–1200. doi: 10.1038/bjc.2014.382

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Copyright © 2014 Cancer Research UK

From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Immunohistochemical staining of NOB1 in RCC specimens and normal renal tissues. NOB1 immunohistochemical staining was performed on different types of RCCs and normal renal tissues, and representative images are shown. (A and B) H&E staining of RCC tissue (magnification, left × 100, right × 200). (C and D) Immunohistochemical staining of normal renal tissue, staining revealed that no significant staining was observed in normal renal tissues (magnification, left × 200, right × 400), and with the increasing of grade I–IV (E–L), renal tissue specimens expressing NOB1 protein. NOB1 staining was stronger in high-grade RCC than that in low-grade RCC.