Table 2.
Frequency of presence of ICD-9-CM codes for signs of HHT recorded among individuals with and without ICD-9-CM code 448.0 in MarketScan Commercial and Supplemental Medicare Databases, 2005–2010 (excluding Michigan)
| Condition | With HHT (N) | % | Without HHT (n) | % | Rate ratio |
|---|---|---|---|---|---|
| Epistaxis | 411 | 34.2 | 294,938 | 0.82 | 42 |
| Brain AVM | 65 | 5.4 | 15,079 | 0.04 | 135 |
| Lung AVM | 173 | 14.4 | 10,285 | 0.03 | 480 |
| Unspecified AVM of vascular system | 152 | 12.6 | 17,441 | 0.05 | 252 |
| Arteriovenous fistula, acquired | 9 | 0.8 | 5,005 | 0.01 | 80 |
| Any AVM | 285 | 23.7 | 45,600 | 0.13 | 182 |
| Upper GI angiodysplasia | 97 | 8.1 | 7,613 | 0.02 | 405 |
| Angiodysplasia of the intestine | 85 | 7.1 | 15,606 | 0.04 | 178 |
| Hemorrhage of GI tract, unspecified | 212 | 17.6 | 274,404 | 0.76 | 23 |
| Anemia | 602 | 50.0 | 1,997,615 | 5.55 | 9 |
| Aneurysm or intracerebral hemorrhage | 35 | 2.9 | 54,313 | 0.15 | 19 |
| Hemoptysis | 46 | 3.8 | 72,879 | 0.20 | 19 |
| Dyspnea | 382 | 31.8 | 3,143,068 | 8.73 | 4 |
| Telangiectasia | 120 | 10.0 | 43,849 | 0.12 | 83 |
AVM, arteriovenous malformation; GI, gastrointestinal; HHT, hereditary hemorrhagic telangiectasia; ICD-9-CM, International Classification of Disease, 9th Revision, Clinical Modification.