Table 3.
Frequency by age of presence of ICD-9-CM codes for signs of HHT recorded among individuals with HHT (ICD-9-CM 448.0) in MarketScan Commercial and Supplemental Medicare Databases, 2005–2010 (excluding Michigan)
| Condition | <30 years (n = 160)
|
30–59 years (n = 621)
|
≥60 years (n = 422)
|
|||
|---|---|---|---|---|---|---|
| n | % | n | % | n | % | |
| Epistaxis | 30 | 18.8 | 209 | 33.7 | 172 | 40.8 |
|
| ||||||
| Brain AVM | 18 | 11.3 | 35 | 5.6 | 12 | 2.8 |
|
| ||||||
| Lung AVM | 33 | 20.6 | 99 | 15.9 | 41 | 9.7 |
|
| ||||||
| Unspecified AVM of vascular system | 18 | 11.3 | 82 | 13.2 | 52 | 12.3 |
|
| ||||||
| Arteriovenous fistula, acquired | 0 | — | 5 | 0.8 | 4 | 1.0 |
|
| ||||||
| Any AVM | 52 | 32.5 | 154 | 24.8 | 79 | 18.7 |
|
| ||||||
| Upper GI angiodysplasia | 1 | 0.6 | 49 | 7.9 | 47 | 11.1 |
|
| ||||||
| Angiodysplasia of the intestine | 2 | 1.3 | 39 | 6.3 | 44 | 10.4 |
|
| ||||||
| Hemorrhage of GI tract, unspecified | 8 | 5.0 | 86 | 13.9 | 118 | 28.0 |
|
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| Anemia | 23 | 14.4 | 304 | 49.0 | 275 | 65.2 |
|
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| Aneurysm or intracerebral hemorrhage | 4 | 2.5 | 12 | 1.9 | 19 | 4.5 |
|
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| Hemoptysis | 6 | 3.8 | 19 | 3.1 | 21 | 5.0 |
|
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| Dyspnea | 37 | 23.1 | 175 | 28.2 | 170 | 40.3 |
|
| ||||||
| Telangiectasia | 17 | 10.6 | 57 | 9.2 | 46 | 10.9 |
AVM, arteriovenous malformation; GI, gastrointestinal; HHT, hereditary hemorrhagic telangiectasia; ICD-9-CM, International Classification of Disease, 9th Revision, Clinical Modification.