Table 4.
Frequency of presence of combinations of ICD-9-CM codes suggestive of HHT recorded among individuals with and without ICD-9-CM code 448.0 in MarketScan Commercial and Supplemental Medicare Databases, 2005–2010 (excluding Michigan)
| Condition | With HHT code (n) | % | Without HHT code (n) | % | Rate ratio |
|---|---|---|---|---|---|
| Epistaxis + brain AVM | 27 | 2.2 | 347 | 0.001 | 2,282 |
| Epistaxis + lung AVM | 60 | 5.0 | 231 | 0.001 | 7,791 |
| Epistaxis + unspecified AVM of vascular system | 70 | 5.8 | 515 | 0.001 | 4,054 |
| Epistaxis + upper GI angiodysplasia | 33 | 2.7 | 427 | 0.001 | 2,276 |
| Epistaxis + telangiectasia | 59 | 4.9 | 847 | 0.002 | 2,082 |
| Brain AVM + lung AVM | 27 | 2.2 | 44 | 0.000 | 17,997 |
| Brain AVM + upper GI angiodysplasia | 8 | 0.7 | 32 | 0.000 | 7,873 |
| Lung AVM + unspecified AVM of vascular system | 68 | 5.7 | 162 | 0.000 | 12,664 |
| Lung AVM + upper GI angiodysplasia | 12 | 1.0 | 9 | 0.000 | 39,992 |
| Lung AVM + angiodysplasia of the intestine | 4 | 0.3 | 7 | 0.000 | 15,426 |
AVM, arteriovenous malformation; GI, gastrointestinal; HHT, hereditary hemorrhagic telangiectasia; ICD-9-CM, International Classification of Disease, 9th Revision, Clinical Modification.