Table 1.
Numbers of live births, cases of newborns with SCD identified via Newborn Screening Program and incidence rates of SCD by demographic characteristics and maternal nativity (New York State live birth cohort, 2000–2008)
| All newbornsa |
US-born mothers |
Foreign-bornb mothers |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Live births | SCD | Live births | SCD | Live births | SCD | ||||
|
|
|
|
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| Characteristic | n (%) | n (%) | Ratec | n (%)d | n (%)d | Ratec | n (%)d | n (%)d | Ratec |
| Total | 2,189,867 (100.0) | 1,911 (100.0) | 1,146 | 1,407,478 (64.3) | 839 (43.9) | 1,678 | 755,566 (34.5) | 1,055 (55.2) | 716 |
| Maternal race/ethnicity | |||||||||
| Non-Hispanic white |
1,041,168 (47.5) | 25 (1.3) | 41,647 | 896,751 (86.1) | 16 (64.0) | 56,047 | 127,375 (12.2) | 9 (36.0) | 14,153 |
| Non- Hispanic black |
378,524 (17.3) | 1,644 (86.0) | 230 | 233,848 (61.8) | 743 (45.2) | 315 | 142,300 (37.6) | 889 (54.1) | 160 |
| Hispanic | 568,150 (25.9) | 220 (11.5) | 2,583 | 234,788 (41.3) | 74 (33.6) | 3,173 | 329,397 (58.0) | 142 (64.5) | 2,320 |
| Asian/Pacific Islander |
180,649 (8.2) | 7 (0.4) | 25,807 | 12,022 (6.7) | 0 (0.0) | — | 166,035 (91.9) | 6 (85.7) | 27,673 |
| Other/unknown | 21,376 (1.0) | 15 (0.8) | 1,425 | 11,331 (53.0) | 6 (40.0) | 1,889 | 9,197 (43.0) | 9 (60.0) | 1,022 |
| Residence | |||||||||
| New York City | 1,032,414 (47.1) | 1,325 (69.3) | 779 | 457,679 (44.3) | 514 (38.8) | 890 | 570,212 (55.2) | 802 (60.5) | 711 |
| Upstate New York |
1,157,453 (52.9) | 586 (30.7) | 1,975 | 931,061 (80.4) | 325 (55.5) | 2,865 | 204,092 (17.6) | 253 (43.2) | 807 |
| Birth year period | |||||||||
| 2000–2002 | 746,794 (34.1) | 670 (35.1) | 1,115 | 485,904 (65.1) | 287 (42.8) | 1,693 | 249,296 (33.4) | 375 (56.0) | 665 |
| 2003–2005 | 727,015 (33.2) | 606 (31.7) | 1,200 | 463,932 (63.8) | 277 (45.7) | 1,675 | 252,948 (34.8) | 325 (53.6) | 778 |
| 2006–2008 | 716,058 (32.7) | 635 (33.2) | 1,128 | 457,642 (63.9) | 275 (43.3) | 1,664 | 253,322 (35.4) | 355 (55.9) | 714 |
| Infant sexe | |||||||||
| Male | 1,121,707 (51.2) | 955 (50.0) | 1,175 | 720,042 (64.2) | 434 (45.4) | 1,659 | 387,826 (34.6) | 516 (54.0) | 752 |
| Female | 1,068,124 (48.8) | 956 (50.0) | 1,117 | 687,414 (64.4) | 405 (42.4) | 1,697 | 367,734 (34.4) | 539 (56.4) | 682 |
| Birth weighte | |||||||||
| <2,500 g | 175,204 (8.0) | 194 (10.2) | 903 | 117,111 (66.8) | 94 (48.5) | 1,246 | 55,450 (31.6) | 99 (51.0) | 560 |
| ≥2,500 g | 2,013,426 (91.9) | 1,713 (89.6) | 1,175 | 1,289,272 (64.0) | 744 (43.4) | 1,733 | 700,009 (34.8) | 953 (55.6) | 735 |
| Gestational agee | |||||||||
| <37 weeks | 207,772 (9.5) | 228 (11.9) | 911 | 141,184 (68.0) | 104 (45.6) | 1,358 | 63,598 (30.6) | 123 (53.9) | 517 |
| ≥37 weeks | 1,977,870 (90.3) | 1,681 (88.0) | 1,177 | 1,263,244 (63.9) | 733 (43.6) | 1,723 | 691,006 (34.9) | 932 (55.4) | 741 |
| Pluralitye | |||||||||
| Single | 2,108,048 (96.3) | 1,859 (97.3) | 1,134 | 1,348,333 (64.0) | 812 (43.7) | 1,661 | 734,109 (34.8) | 1,030 (55.4) | 713 |
| Multiple | 81,816 (3.7) | 52 (2.7) | 1,573 | 59,142 (72.3) | 27 (51.9) | 2,190 | 21,457 (26.2) | 25 (48.1) | 858 |
| Maternal agee | |||||||||
| ≤19 years | 163,666 (7.5) | 190 (9.9) | 861 | 122,770 (75.0) | 141 (74.2) | 871 | 39,288 (24.0) | 49 (25.8) | 802 |
| 20–34 years | 1,557,111 (71.1) | 1,366 (71.5) | 1,140 | 992,578 (63.7) | 592 (43.3) | 1,677 | 545,877 (35.1) | 765 (56.0) | 714 |
| >35 years | 468,914 (21.4) | 355 (18.6) | 1,321 | 292,092 (62.3) | 106 (29.9) | 2,756 | 170,395 (36.3) | 241 (67.9) | 707 |
SCD, sickle cell disease.
a
Includes births to mothers of unknown birth countries.
b
Puerto Rico, which is a US Commonwealth, was treated as a separate country for the purpose of this analysis.
c
One in number of live births.
d
Row percentage.
e
Records with unknown values were not included.