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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Ann Neurol. 2015 Feb 9;77(3):399–414. doi: 10.1002/ana.24332

Figure 3. Biodistribution of scAAV9-shSMN and scAAV9-SMN vectors in the CNS and major peripheral organs after intracisternal injection.

Figure 3

Total DNA was purified from various regions of the (A) brain, (B) spinal cord and (C) peripheral organs. Vector genome (vg) copy numbers for each vector were determined using ddPCR with primers specific to GFP or human SMN (and normalized to pig GAPDH).