Table 3. ORs and 95% CIs for TV watching and risk of adenoma by anatomic location, HPFS 1988–2008.
Sitting while watching (h per week) |
||||||
---|---|---|---|---|---|---|
0–6 | 7–13 | 14–20 | 21+ | Ptrend | Per 14-h per week increment | |
Proximal colon | ||||||
No. of cases (n=2257) | 824 | 809 | 445 | 179 | ||
Age adjusteda | 1.00 (ref.) | 1.07 (0.97–1.18) | 1.22 (1.08–1.37) | 1.22 (1.03–1.44) | <0.001 | 1.24 (1.09–1.42) |
Multivariateb | 1.00 (ref.) | 1.04 (0.94–1.15) | 1.17 (1.04–1.32) | 1.17 (0.98–1.38) | 0.005 | 1.13 (1.04–1.24) |
Multivariateb with physical activity and BMI | 1.00 (ref.) | 1.04 (0.94–1.15) | 1.16 (1.03–1.31) | 1.15 (0.97–1.37) | 0.01 | 1.12 (1.03–1.23) |
Distal colon | ||||||
No. of cases (n=2092) | 738 | 781 | 402 | 171 | ||
Age adjusteda | 1.00 (ref.) | 1.16 (1.05–1.29) | 1.17 (1.03–1.32) | 1.19 (1.00–1.42) | 0.003 | 1.14 (1.05–1.24) |
Multivariateb | 1.00 (ref.) | 1.12 (1.01–1.24) | 1.09 (0.96–1.24) | 1.08 (0.99–1.17) | 0.10 | 1.08 (0.99–1.17) |
Multivariateb with physical activity and BMI | 1.00 (ref.) | 1.12 (1.01–1.24) | 1.09 (0.96–1.24) | 1.10 (0.93–1.31) | 0.11 | 1.07 (0.98–1.17) |
Rectum | ||||||
No. of cases (n=734) | 250 | 266 | 161 | 57 | ||
Age adjusteda | 1.00 (ref.) | 1.17 (0.99–1.40) | 1.38 (1.13–1.69) | 1.18 (0.88–1.58) | 0.004 | 1.22 (1.07–1.39) |
Multivariateb | 1.00 (ref.) | 1.13 (0.95–1.35) | 1.30 (1.06–1.60) | 1.10 (0.82–1.48) | 0.03 | 1.16 (1.01–1.33) |
Multivariateb with physical activity and BMI | 1.00 (ref.) | 1.13 (0.95–1.35) | 1.30 (1.06–1.59) | 1.10 (0.82–1.48) | 0.04 | 1.16 (1.01–1.33) |
Abbreviations: BMI=body mass index; CI=confidence interval; HPFS=Health Professionals Follow-up Study; OR=odds ratio; ref.=referent.
Adjusted for age, time period of endoscopy, number of reported endoscopies, time since most recent endoscopy, and reason for current endoscopy.
Additionally adjusted for family history of colorectal cancer, history of diabetes, height, alcohol intake, smoking, aspirin use, total calorie, folate, calcium intake, and red and processed meat intake.