Table 3. Diagnostic accuracy for recurrence.

		Low risk group (compared with other groups)			High risk group (compared with other groups)
RSS	Diagnostic accuracy statistics	Value	Low 95% CI	High 95% CI	Value	Low 95% CI	High 95% CI
PORTEC-1 (Creutzberg et al, 2000a)	Sensitivity	0.132	0.074	0.216	0.451	0.357	0.545
	Specificity	0.647	0.636	0.664	0.790	0.772	0.809
	PPV	0.069	0.039	0.112	0.297	0.236	0.360
	NPV	0.791	0.777	0.811	0.880	0.859	0.900
	ODA	0.562			0.734
GOG-99 (Keys et al, 2004)	Sensitivity	0.275	0.193	0.371	0.440	0.347	0.534
	Specificity	0.448	0.432	0.467	0.803	0.785	0.822
	PPV	0.089	0.063	0.121	0.305	0.241	0.371
	NPV	0.758	0.731	0.790	0.879	0.859	0.899
	ODA	0.420			0.743
SEPAL (Todo et al, 2010)	Sensitivity	0.187	0.118	0.278	0.264	0.187	0.350
	Specificity	0.522	0.508	0.540	0.881	0.866	0.898
	PPV	0.071	0.045	0.106	0.304	0.215	0.403
	NPV	0.765	0.745	0.791	0.859	0.844	0.875
	ODA	0.457			0.769
ESMO (Colombo et al, 2013)	Sensitivity	0.176	0.109	0.266	0.451	0.359	0.542
	Specificity	0.496	0.482	0.513	0.844	0.826	0.862
	PPV	0.064	0.040	0.097	0.363	0.289	0.437
	NPV	0.753	0.733	0.780	0.886	0.867	0.905
	ODA	0.467			0.773
ESMO modifieda (Bendifallah et al, 2014)	Sensitivity	0.179	0.109	0.273	0.452	0.357	0.548
	Specificity	0.508	0.494	0.527	0.837	0.818	0.856
	PPV	0.067	0.041	0.103	0.355	0.280	0.430
	NPV	0.757	0.736	0.785	0.885	0.865	0.905
	ODA	0.453			0.776

Abbreviations: ESMO=European Society for Medical Oncology; GOG=Gynecologic Oncology Group; NPV=negative predictive values; ODA=overall diagnostic accuracy; PORTEC=Post Operative Radiation Therapy in Endometrial Carcinoma; PPV=positive predictive values; SEPAL=Survival effect of para-aortic lymphadenectomy.

^aIntermediate-risk ESMO/LVSI+ and high risk groups compared with intermediate risk ESMO/LVSI- and low risk.