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. 2015 Feb 3;112(5):809–818. doi: 10.1038/bjc.2015.8

Table 3. Distribution of findings by imaging at the time of tumour marker increase.

  Patients
Detected lesions, N (%) N=44 (100)
Distant metastasesa 29 (65.9)
Local recurrenceb 1 (2.3)
Secondary malignancies 6 (13.6)
Benign lesions 9 (20.5)
Metastatic sites, N (%) N=29 (100)
Bone 18 (62.1)
Liver 8 (27.6)
Lung 7 (24.1)
Lymph node 12 (41.4)
Others 11 (37.9)
Visceral diseasec 12 (41.4)
Only bone lesions 10 (34.5)
Numbers of metastatic sites, N (%) N=29 (100)
1 organ 14 (48.3)
2 organs 7 (24.1)
>2 organs 8 (27.6)
Limited diseased 7 (24.1)
Diffuse metastatic disease 20 (69.0)
Secondary malignancies, N (%) N=6 (100)
Ovarian cancere 2 (33.3)
Uterine cancer 1 (16.7)
Gastric cancer 1 (16.7)
Non-small cell lung cancer 1 (16.7)
Multiple myeloma 1 (16.7)
Carcinoma of the parotid gland 1 (16.7)
Benign lesions, N (%) N=9 (100)
Benign lesion of the lung 1 (11.1)
Benign lymph node 1 (11.1)
Breast implant rupture 2 (22.2)
Pancreatitis 1 (11.1)
Cyst of the ovarian 1 (11.1)
Diarrhoea 1 (11.1)
No evidence of disease 2 (22.2)
a

The liver metastases of one patient were detected 6 months later in follow-up imaging.

b

One patient had both local recurrence and a secondary malignancy.

c

Involvement of the lung and/or liver.

d

Less than four malignant lesions to a single organ.

e

One patient had both an primary cancer of the uterine and an ovarian cancer.