Table 2. Patient characteristics and distribution according to Ki67 expression in the test cohort (n=187).
|
Low Ki67 |
High Ki67 |
All patients |
|||||
|---|---|---|---|---|---|---|---|
| Characteristics | Numbers | % | Numbers | % | Numbers | % | P-value |
|
Age, Years | |||||||
| ⩽61.5 | 50 | 53.2 | 44 | 46.8 | 94 | 50.3 | NS* |
| >61.5 | 45 | 48.4 | 48 | 51.6 | 93 | 49.7 | — |
|
Sex | |||||||
| Female | 25 | 62.5 | 15 | 37.5 | 40 | 21.4 | NS* |
| Male | 70 | 47.6 | 77 | 52.4 | 147 | 78.6 | — |
|
Histology | |||||||
| Epithelioid | 81 | 51.9 | 75 | 48.1 | 156 | 83.4 | NS* |
| Non- Epithelioid | 14 | 45.2 | 17 | 54.8 | 31 | 16.6 | — |
|
Stage# | |||||||
| early stage | 22 | 64.7 | 12 | 35.3 | 34 | 21.7 | NS* |
| late stage | 60 | 48.8 | 63 | 51.2 | 123 | 78.3 | — |
|
Treatment# | |||||||
| Surgery alone | 12 | 46.2 | 14 | 53.8 | 26 | 16.6 | 0.02* |
| Best supportive care | 13 | 39.4 | 20 | 60.6 | 33 | 21 | — |
| Chemo and/or Radiotherapy | 24 | 45.3 | 29 | 54.7 | 53 | 33.8 | — |
| Multimodal treatment | 32 | 71.1 | 13 | 28.9 | 45 | 28.7 | — |
|
Surgery# | |||||||
| Surgery | 44 | 62 | 27 | 38 | 71 | 45.2 | 0.02* |
| No Surgery | 37 | 43 | 49 | 57 | 86 | 54.8 | — |
|
Induction Therapy# | |||||||
| Induction | 25 | 75.8 | 8 | 24.2 | 33 | 21 | 0.01* |
| Chemo-naïve at sampling time | 56 | 45.2 | 68 | 54.8 | 124 | 79 | — |
Abbreviations: NS=not significant.
‘*'=two-sided χ2-test; ‘#'=missing cases: n=30 (16.0%).