Table 2.
Hereditary nature and total affected family members in cases with congenital anomalies (n=74)
| Anomaly type | Cases | Hereditary nature | Familial cases | |||
|---|---|---|---|---|---|---|
| Sporadic | Familial | Total no. of affected in all families | Affected male/female ratio | |||
| Limb defects | 51 | 42 | 9 | 27 | 7:20 | |
| Club-thumb | 18 | 16 | 2 | 5 | 1:4 | |
| Brachydactyly | 12 | 7 | 5 | 14 | 3:11 | |
| Camptodactyly | 8 | 7 | 1 | 6 | 2:4 | |
| Clinodactyly | 7 | 6 | 1 | 2 | 1:1 | |
| Polydactyly | 4 | 4 | ||||
| Synpolydactyly | 1 | 1 | ||||
| Brachy-syndactyly | 1 | 1 | ||||
| Other anomalies | 23 | 21 | 2 | 9 | 5:4 | |
| Deaf-mute | 7 | 6 | 1 | 3 | 1:2 | |
| Stuttering/mute | 3 | 3 | ||||
| Microtia | 3 | 3 | ||||
| Mental retardation | 3 | 3 | ||||
| Squint eyes | 2 | 2 | ||||
| Orofacial defects | 2 | 2 | ||||
| Hand-feet allergy | 2 | 1 | 1 | 6 | 4:2 | |
| Trembling body | 1 | 1 | ||||
| Total | 74 | 63 | 11 | 36 | 12/24 | |