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. 2015 Jun 3;5:10806. doi: 10.1038/srep10806

Figure 6. The comparison of expression level and methylation status of target genes in HIV infected patients with high and low viral load.

Figure 6

The mRNA expression levels of IGFBP6 (a) and SATB2 (b) were analyzed in 5 HIV infected subjects with different viral load. * P < 0.05, Paired Student T test. Data represent means ±SD from at least 2 independent experiments. HIV VL < 500 indicated that the sample was collected when the viral load of the subject was lower than 500 copies/ml; HIV VL > 20,000 indicated the viral load was higher than 20,000 copies/ml. Methylation status of IGFBP6 and SATB2 (c) were checked by MSP. M, PCR for CpG-methylated DNA; UM, PCR for CpG-unmethylated DNA. If the viral load of the sample was lower than 500 copies/ml or higher than 20,000 copies/ml, it would be termed as “HIV −”or “HIV +”, respectively. Fully uncut gel images are shown in Supplementary Figures.