Table 1. Annotation analysis of DMRs in CpGi-promoter region from HIV+ twin.
| Ontology type | Term | p-Value |
|---|---|---|
| GOTERM_BP_FAT | regulation of transcription | 5.50E-04 |
| cellular macromolecular complex subunit organization | 6.10E-04 | |
| actin polymerization or depolymerization | 9.00E-04 | |
| GOTERM_CC_FAT | non-membrane-bounded organelle | 1.20E-08 |
| intracellular non-membrane-bounded organelle | 1.20E-08 | |
| cytosol | 3.60E-06 | |
| intracellular organelle lumen | 1.20E-05 | |
| membrane-enclosed lumen | 1.70E-05 | |
| organelle lumen | 3.20E-05 | |
| microtubule cytoskeleton | 3.80E-05 | |
| protein-DNA complex | 2.10E-04 | |
| ribonucleoprotein complex | 7.30E-04 | |
| nuclear lumen | 9.20E-04 | |
| GOTERM_MF_FAT | transition metal ion binding | 3.40E-06 |
| DNA binding | 8.20E-06 | |
| zinc ion binding | 1.60E-05 | |
| KEGG_PATHWAY | hsa03010:Ribosome | 7.85E-03 |
| hsa00240:Pyrimidine metabolism | 1.66E-02 | |
| hsa00100:Steroid biosynthesis | 4.04E-02 |
a. Detailed data are shown in Supplemental Table S3.
b. Ontology types of BP, CC and MF represents biological process, cellular component and molecular function. KEGG represents KEGG pathway database.