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Inhibition of GSK3β improves movement ability of mnd2 mice. The rotarod test showed that the performance of mnd2 mice was severely deteriorated compared with wide-type mice treated with DMSO; however, the performance was significantly improved in SB216763-treated mnd2 mice of 16, 20, 25 and 30 days old compared with DMSO-treated mnd2 mice. There was no significant difference of wide-type mice treated with DMSO or SB216763. n=10 per group, *P<0.05; Δ, no significance; one-way ANOVA
