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. 2014 Aug 7;5(8):e1362. doi: 10.1038/cddis.2014.331

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Copyright © 2014 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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The effect of PILO on PARP1 and GFAP expression ex vivo. In the DG, ACSF+PILO decreased PARP1 expression in astrocytes, but increased it in astrocytes in the CA1 region. In the PC, ACSF+PILO reduced PARP1 expression and the number of GFAP-positive astrocytes. Bar=25 μm (DG and CA1) and 12.5 μm (PC)