Figure 5.
Construction of p65/RelA mutants at candidate caspase-dependent cleavage sites. (a) p65/RelA constructs with mutations in the candidate caspase-dependent cleavage sites and p65/RelA fragments 1–361 and 362–549 generated by p65/RelA cleavage at the D361 site. (b) Putative caspase-3 (bold underlined) and caspase-6 (bold italic) cleavage sites in the mouse p65/RelA protein