Figure 1.
A. Renin expression in juxtaglomerular cells (insert in red and arrow) and in collecting ducts (red). Brown color indicates aquaporin-2 (AQP-2) immunostaining, which is a specific marker for principal cells of the collecting duct. B. Renin immunolabeling in collecting ducts of a control rat; C. Renin is augmented in collecting ducts of Ang II infused rats. D. In Angiotensin II infused rats AT1 receptor antagonist blunted this effect. (modified from Prieto-Carrasquero et al., 2004; 2005).