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Immunocytochemical evidence of the expression of renin in principal cells (red) and (pro)renin receptor (green) in intercalated cells in M-1 collecting duct cell line. Blue (DAPI; 4′,6-diamidino-2-phenylindole) is a nuclei marker. The image demonstrates close interaction between principal cells; the source of renin and prorenin and intercalated cells that expressing the (pro)renin receptor.
