Table 2.

Changes in estimated glomerular filtration rate from baseline to one year in treatment groups

Variable	Atorvastatin 10 mg (n = 4,696)	Atorvastatin 80 mg (n = 4,680)	Total (n = 9,376)	p Value*
Estimated glomerular filtration rate (ml/min/1.73 m2)
Baseline	65.6 ± 11.4	65.0 ± 11.3	65.3 ± 11.3	0.018
1 year	65.7 ± 11.8	66.6 ± 11.9	66.1 ± 11.9	0.0002
Change from baseline to 1 year	0.1 ± 6.8	1.5 ± 7.0	0.8 ± 6.9	<0.0001
Comparison of 1 year to baseline within treatment group†	0.10 (−0.09 to 0.30)	1.48 (1.29–1.67)	0.79 (0.65–0.93)
p Value	0.29	<0.0001	<0.0001

^*Values for between-treatment estimated glomerular filtration rate were based on 2-sample t tests.

^†Values are presented as least square means or means difference (95% confidence interval); values for within- and between-treatment comparisons were based on an analysis of covariance model comparing patients with to those without heart failure hospitalization that was adjusted for baseline estimated glomerular filtration rate.