Table 3.

Changes in estimated glomerular filtration rate from baseline to one year in patients with and without subsequent heart failure hospitalization

Variable	HF Hospitalization		p Value*
	No (n = 9,158)	Yes (n = 218)
Modification of Diet in Renal Disease estimated glomerular filtration rate (ml/min/1.73 m2)
Baseline	65.4 ± 11.2	61.3 ± 13.9	<0.0001
1 year	66.2 ± 11.8	61.2 ± 14.5	<0.0001
Change from baseline to 1 year	0.8 ± 6.9	−0.1 ± 7.9	0.0015
Comparison of 1 year to baseline within treatment group†	0.82 (0.69–0.96)	−0.65 (−1.54 to 0.25)
p Value	<0.0001	0.16

^*Values for between-treatment estimated glomerular filtration rate were based on 2-sample t tests.

^†Least square means or means difference (95% confidence interval) for within- and between-treatment comparisons were based on an analysis of covariance model comparing patients with to those without heart failure hospitalization that was adjusted for baseline estimated glomerular filtration rate.