Table 3.

Analyses results for the HNCS and survival time of the CHANCE study

		Simultaneous			Separate
Parameter		Est.	ESE	P-value	Est.	ESE	P-value
< HNCS QoL longitudinal model >
Intercept	β 0	.744	.538	.167	1.190	.390	.002
Race (ref= White)
– African American	β 1	.564	.229	.014	.511	.256	.047
# of 12 oz. beers consumed per week (ref=30 or more)
– None	β 2	.636	.269	.018	.622	.300	.038
– less than 1	β 3	.830	.357	.020	.735	.396	.064
– 1 to 4	β 4	1.302	.294	<.001	1.268	.326	<.001
– 5 to 14	β 5	1.060	.251	<.001	1.018	.279	<.001
– 15 to 29	β 6	.601	.289	.037	.547	.327	.095
Household income (ref= level1: 0–10K)
– level2: 20–30K	β 7	−.271	.231	.241	−.328	.258	.204
– level3: 40–50K	β 8	.297	.255	.245	.250	.282	.376
– level4: ≥ 60K	β 9	1.199	.274	<.001	1.045	.286	<.001
Radiation therapy (ref= No)
– Yes	β 10	−1.132	.260	<.001	−1.048	.280	<.001
Tumor stage (ref= I)
– II	β 11	−.416	.300	.166	−.352	.330	.286
– III	β 12	−1.335	.284	<.001	−1.198	.314	<.001
– IV	β 13	−1.175	.254	<.001	−1.057	.277	<.001
# of persons supported by household income	β 14	−.189	.084	.025
BMI	β 15	.041	.015	.007
Total # of medical conditions reported	β 16	−.175	.080	.030
Time at survey measurement (years)	β 17	.241	.066	<.001	.254	.067	<.001
variance of random effects	${\sigma }_b^2$	.303	.173	.013	1.169	.257
< Hazards model >
Random effect coefficient	ψ	−1.427	.946	.131
# of 12 oz. beers consumed per week (ref=30 or more)
– None	γ 1	−.772	.386	.045
– less than 1	γ 2	−.155	.426	.715
– 1 to 4	γ 3	−.802	.414	.053
– 5 to 14	γ 4	−1.076	.383	.005
– 15 to 29	γ 5	−.591	.399	.139
Household income (ref= level1: 0–10K)
– level2: 20–30K	γ 6	−.218	.294	.459	−.219	.263	.406
– level3: 40–50K	γ 7	−.941	.371	.011	−.928	.331	.005
– level4: ≥ 60K	γ 8	−1.463	.401	<.001	−1.393	.358	<.001
Tumor stage (ref= I)
– II	γ 9	−.199	.465	.668	−.295	.435	.498
– III	γ 10	.235	.433	.588	.136	.389	.727
– IV	γ 11	1.059	.360	.003	.914	.295	.002
Total # of medical conditions reported	γ 12	.256	.110	.020	.205	.091	.025

P-value for testing ${\sigma }_b^2$ being zero is based on a mixture of 0 and χ² distribution with 1 degree of freedom with equal mixing probabilities.