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. Author manuscript; available in PMC: 2015 Jun 3.
Published in final edited form as: Brain. 2013 Dec 12;137(Pt 2):565–575. doi: 10.1093/brain/awt337

Figure 4.

Figure 4

Relationship between striatal dopamine and insular D2 levels in Parkinson’s disease with MCI. (A) Parametric map displaying region of significant positive relationship between associative striatal dopamine preservation and D2 binding in the right anterior insula (x = 40, y = 12, z = 10, k = 59, T = 6.34 P < 0.05 FWE small volume corrected, R2 = 0.679). (B) 11C-FLB 457 BPND extracted from cluster in the right insula of the parametric map and plotted against 11C-DTBZ BPND from the associative striatum in patients with Parkinson’s disease with MCI demonstrating a positive correlation.