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. 2015 Jun 3;10(6):e0127755. doi: 10.1371/journal.pone.0127755

Fig 5. Identification of disease-associated genes in the ALI system.

Fig 5

Venn diagram depicting the number of genes dysregulated in the inflamed esophageal tissue of patients with active eosinophilic esophagitis (EoE) compared to healthy (NL) controls (P < 0.05, fold change > 2, n = 1,607) and the number of genes altered in the air-liquid interface (ALI) after prolonged IL-13 exposure (day 14 [IL-13] compared to day 14 [untx]; P < 0.05, fold change > 2; n = 781) (A). Clustered heatmap showing the log2 FPKM values (B) and fold change correlation (C) of the 257 genes similarly dysregulated in the ALI after prolonged IL-13 exposure and in the inflamed esophageal tissue of patients with active eosinophilic esophagitis (EoE). Untx, untreated.