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. 2015 Jun 3;10(6):e0127755. doi: 10.1371/journal.pone.0127755

Fig 7. Decreased KRT78 expression in EoE.

Fig 7

Clustered heatmap showing the log2 FPKM values of differentially expressed keratins in the esophagus of healthy controls (NL) and patient with active EoE (P < 0.05, fold change > 2.0) (A). The right panel depicts the FPKM of corresponding keratin genes in log scale. Quantitative PCR analysis of KRT78 expression in esophageal biopsies from NL (n = 23) and patients with active EoE (n = 49) (B). Correlation between esophageal expression levels of KRT78 and IL13 in NL (n = 23) and patients with active EoE (n = 34) (C). Quantitative PCR analysis of KRT78 expression in esophageal biopsies from NL (n = 11) and patients with active EoE (n = 12) and in disease remission (n = 11) (D). Western blot analysis of KRT78 (upper panel) and GAPDH (lower panel) expression in esophageal biopsy protein lysates from NL (n = 3) and patients with active EoE (n = 4) (E). Data in (B) and (D) are represented as mean with SEM. *, P < 0.05; ***, P < 10–3; ****, P < 10-4. Ns, not significant.