Table 1. Clinical and microbiological characteristics of 8 patients in L511P cluster.
| Patient | Age | Sex | HIV status | Category I treatment outcome | Category II treatment outcome | Category IV treatment outcome | rpoB mutations | Resistance to 1 μg/ml RIF (MGIT) | RIF MIC (μg/ml) |
|---|---|---|---|---|---|---|---|---|---|
| A | 28 | f | N | failed | failed | cured | L511P, D516C | RESISTANT | >8 |
| B | 34 | f | N | failed | failed | cured | L511P, M515T | susceptible | [0.25–0.5] |
| C | 10 m | m | N | … | … | cured | L511P, M515T | susceptible | [0.25–0.5] |
| D | 30 | m | P | failed | cured* | … | L511P | susceptible | 0.125 |
| E | 28 | f | P | cured | … | … | L511P | susceptible | [0.125–0.25] |
| F | 21 | f | N | … | … | cured | L511P | susceptible | 0.125 |
| G | 18 | m | N | failed** | … | … | L511P | susceptible | n.d. |
| H | 30 | f | N | unknown | unknown | … | L511P | susceptible | n.d. |
* Delayed response
** Deceased
n.d. Not determined