Table 2. Biomarkers that discriminate between Relapsing-Remitting and Progressive Clinical forms of MS by ROC curves.
RR-MS vs Progressive MS | AUC | (95% CI) | p value | Cut off (pg/ml) |
---|---|---|---|---|
HGF | 0.702 | (0.604–0.799) | <0.0002 | 387 |
Eotaxin/CCL11 | 0.755 | (0.662–0.849) | <0.0001 | 132 |
MCP-1/CCL2 | 0.721 | (0.626–0.816) | <0.0001 | 550 |
Rantes/CCL5 | 0.792 | (0.707–0.876) | <0.0001 | 5536 |
EGF | 0.689 | (0.592–0.786) | 0.0005 | 66 |
MIP-1β/CCL4 | 0.702 | (0.607–0.798) | <0.0002 | 109 |
The areas under the curve (AUC), 95% Confidence Interval (95% CI) and p value for each analyte are depicted in Table 2.