Figure 2.
6-4PP dosimetry curves. Dose–response curves for the formation of 6-4 pyrimidine-pyrimidone photoproduct in NHF1 exposed to a solar simulator (UVA–UVB, closed circles), UVB only (open squares) or UVC (open diamonds) as a function of cyclobutane pyrimidine dimers density. The 6-4PP density produced by UVC was statistically different from that produced by irradiation with a solar simulator (P = 0.04 by linear regression analysis). Both lesions were quantified in each sample by radioimmunoassay (n = 3–4, mean ± SEM).
