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. Author manuscript; available in PMC: 2015 Jun 3.
Published in final edited form as: Photochem Photobiol. 2013 Nov 28;90(1):145–154. doi: 10.1111/php.12194

Figure 6.

Figure 6

Inhibition of DNA strand growth by UVC or UVA–UVB. Representative velocity sedimentation analysis of nascent DNA from NHF1 cells exposed to high fluences of a) UVC (0, 5, 8, or 12 J m−2) or b) UVA–UVB (0, 18.3, 29.2, or 41.6 kJ m−2). Fluences were chosen to induce equal cyclobutane pyrimidine dimers densities (0, 156, 259, or 397 CPD/Mb, respectively). c) Inhibition of DNA strand growth (calculated from the area under curve between the two arrows as compared to sham irradiated) is shown as a function of CPD burden for NHF1 exposed to UVA–UVB (closed circles) or UVC (open diamonds). Figure represents the combination of five different experiments examining increasing irradiation fluences from the UVC or the solar simulator sources. There was no statistical difference in the percent inhibition of DNA strand growth by UVA–UVB or UVC (linear regression analysis, P = 0.59).