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. 2015 Jun 3;10(6):e0128526. doi: 10.1371/journal.pone.0128526

Table 4. Multivariable logistic regression analysis of clinical outcomes.

Time of symptom onset 1-year mortality 30-day mortality Reinfarction Left ventricular systolic dysfunction Killip Class (I vs. II—IV)
OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value
Midnight–6:00 A.M. 1 (reference group) 0.7 1 (reference group) 0.47 1 (reference group) 0.85 1 (reference group) 0.07 1 (reference group) 0.001
6:00 A.M.–Noon 0.73 (0.35–1.49)   0.93 (0.53–1.64)   1.16 (0.50–2.70)   0.83 (0.67–1.02)   0.69 (0.57–0.82)  
Noon–6:00 P.M. 1.07 (0.47–2.44)   1.47 (0.79–2.75)   0.81 (0.30–2.21)   1.05 (0.83–1.33)   0.73 (0.61–0.88)  
6:00 P.M.–Midnight 0.77 (0.35–1.71)   1.20 (0.64–2.23)   1.24 (0.50–3.05)   1.02 (0.80–1.29)   0.88 (0.74–1.05)  

A multivariable logistic regression model adjusting for diabetes prevalence, infarct location (anterior vs. non-anterior) and performance of percutaneous coronary intervention (PCI) was used to determine if time of symptom onset was an independent predictor of secondary outcomes.