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Pathways of C21 steroids synthesis in 21OHD. HSD3B2, 3β-hydroxysteroid dehydrogenase type 2; CYP17A1, 17α-hydroxylase/17,20-lyase; CYB5A, cytochrome b5 type A; CYP11B1, 11β-hydroxylase; CYP11B2, aldosterone synthase; HSD17B5, 17β-hydroxysteroid dehydrogenase type 5.
