Table 2.

Percentages of C₂₁ Steroids in Patient Serum and TART Cell-Conditioned Medium

Steroid	% of Steroids					TART/NAa
	Patient Serum	TART Basal	TART ACTHb	NA Basal	NA ACTH	Basal	ACTH
Progesterone	1.4	6	4.8	0.8	0.5	8.7	11.7
17OHP	78	64	75	8.7	9.8	8.8	9.2
16OHP	6.6	7.7	8.25	1.4	1.5	6.6	6.6
11OHP	0.2	4	1	0.08	0.02	58.5	65
21dF	7	15.5	7	0.46	0.3	41	30
11-Deoxycorticosterone	0.2	0.14	0.05	2.4	1.3	0.07	0.04
11-Deoxycortisol	0.45	0.45	0.24	25	14.1	0.02	0.02
Corticosterone	0.6	0.6	0.8	3.4	5.65	0.2	0.17
Cortisol	4.6	1.75	2.6	41.5	64.5	0.05	0.05
Cortisone	1.9	0.15	0.06	16	2.3	0.01	0.03

Abbreviation: NA, normal adrenal. Medium was collected under basal conditions and after ACTH (10 nmol/L) stimulation. Ratios were calculated by dividing the means of steroid concentrations from three biological replicates for each condition.

^aTART cells from a patient with 21OHD/NA cells. Patient serum is from the same patient before TART excision surgery.

^bUnder these conditions, we estimate a total steroid production rate of approximately 100 ng/10 000 cells/24 h.