Table 1.
Preintervention measure | Sucrose (n = 11) | Aspartame (n = 8) | P value |
---|---|---|---|
Age, y | 27.2 ± 2.0 | 26.5 ± 2.4 | .829 |
BMI, kg/m2 | 25.7 ± 1.0 | 25.8 ± 1.2 | .932 |
Wheaton Chronic Stress Score | 17.7 ± 2.3 | 16.8 ± 2.7 | .784 |
MIST-induced cortisol response, nmol/L Δa | 2.3 ± 1.6 | 1.0 ± 1.9 | .971 |
Total cortisol output (AUC) during the MIST visit, nmol/Lmin | 121.4 ± 13.2 | 130.0 ± 15.4 | .660 |
Naltrexone-induced cortisol response, nmol/L Δa | 0.15 ± 0.13 | 0.10 ± 0.31 | .878 |
Naltrexone-induced nausea response ratinga | 0.50 ± 0.31 | 1.17 ± 0.40 | .207 |
For testing differences in Δ cortisol and nausea, the pretask (ie, MIST; naltrexone) value was included as an independent variable in the statistical model.