Skip to main content
. 2015 Apr 24;12(5):4546–4571. doi: 10.3390/ijerph120504546

Table 4.

Synopsis of Risk Characterization and Interpretation elements for Phase 3 of a CRA for Community, State, and Federal applications.

Risk Characterization and Interpretation Elements Community State Federal
Risk Description
Central Tendency and High-End Individual Risk
Population Risk
Risk to Important Subpopulations
Multiroute chemical risk assessments; poverty and race/ethnicity considerations; children and elderly; mortality/morbidity clusters Sensitive/vulnerable population groups; socioeconomic factors; multiple emissions and discharges; current and future conditions Standards to protect most sensitive populations (e.g., SDWA); aggregate exposure regulations (e.g. FQPA); reasonably anticipated adverse effects (e.g., CWA Sn. 405); primary standards to protect children, elderly, asthmatics
Uncertainty Analysis
Being Explicit about Uncertainty
Uncertainty and Variability
Uncertainty and Risk Addition
Sensitivity Analysis
GIS-based analyses; local health and emissions records; deviations from baseline or more ideal conditions; proxies for exposure; measurements and sensors increase certainty Indicators or surrogates of exposure, such as hazard proximity and air pollution exposure estimates; resolution suitable for targeting and implementation of policy Economic, social, and environmental conditions are interrelated, producing direct, indirect and cumulative effects
Information Provided by CRA Stressor, asset, and resource identification; absolute or relative ranking; remediation options Identification of at-risk individuals or populations; weighting of risk based socio-economic, health, and environmental conditions Systematic, interdisciplinary approaches; integration of natural, social, and environmental sciences and designs
Using the Results of CRA Solution-oriented, data-supported, value-driven decision-making Implementation of exposure and risk reduction actions; source attribution; protective standards for land use or other policies Dose addition with relative potency and toxic equivalency factors or to develop a hazard index; stakeholder feedback and participation to inform research and development that supports local efforts