Table 3.
Sensitivity and specificity of MiniLab® tests for detecting drugs noncompliant with HPLC content analysis (frequency, proportion, and 95% exact confidence interval)
| Antibiotic | Test | Sensitivity | Specificity |
|---|---|---|---|
| Amoxicillin | MiniLab® CT | 0/1 | 19/19 |
| 0% [0.0–97.5] | 100% [82.3–100.0] | ||
| MiniLab® TLC | 0/1 | 17/19 | |
| 0% [0.0–97.5] | 89.5% [66.9–98.7] | ||
| Co-trimoxazole | MiniLab® CT | 0/14 | 1/1 |
| 0% [0.0–23.2] | 100% [0.0–23.2] | ||
| MiniLab® TLC | 2/14 | 1/1 | |
| 14% [1.8–42.8] | 100% [2.5–100.0] |
HPLC = high-performance liquid chromatography; MiniLab® CT = colorimetric test; MiniLab® TLC = semi-quantitative thin layer chromatography.