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. 2015 Jun 3;92(Suppl 6):75–86. doi: 10.4269/ajtmh.14-0544

Table 6.

Percentage of selected ACTs by quantity of stated API for artemisinin component and partner drug

(a) All ACTs analyzed (N = 1,281)
Partner drug
Artemisinin component %API 55–65 65–75 75–85 85–115 115–125 > 125 Total
55–65 < 0.1 0 0.1 < 0.1 < 0.1 0 0.2
65–75 0 0.1 0 < 0.1 0 0 0.2
75–85 0 0 < 0.1 1.7 0.1 0 1.9
85–115 0 0 3.3 87.9 2.7 0.6 94.4
115–125 0 < 0.1 0 1.4 1.5 0 2.9
> 125 0 0 0 0.2 0.1 0 0.3
Total < 0.1 0.2 3.4 91.3 4.5 0.6 100
(b) Alu (N = 504)
Lumefantrine
Artemether drugs %API 55–65 65–75 75–85 85–115 115–125 > 125 Total
55–65 0 0 0 0 0 0 0.0
65–75 0 0 0 0 0 0 0.0
75–85 0 0 0 < 0.1 0 0 < 0.1
85–115 0 0 0.2 96.9 1.0 0 98.0
115–125 0 0 0 1.4 0 0 1.4
> 125 0 0 0 0.6 0 0 0.6
Total 0.0 0.0 0.2 98.9 1.0 0.0 100
(c) Artemisinin–piperaquine (N = 173)
Piperaquine
Artemisinin %API 55–65 65–75 75–85 85–115 115–125 > 125 Total
55–65 0 0 0 0 0 0 0.0
65–75 0 0 0 0 0 0 0.0
75–85 0 0 0 3.6 0 0 3.6
85–115 0 0 0.9 88.5 2.7 4.3 96.4
115–125 0 0 0 0 0 0 0.0
> 125 0 0 0 0 0 0 0.0
Total 0.0 0.0 0.9 92.1 2.7 4.3 100
(d) Artesunate–mefloquine (N = 310)
Mefloquine
Artesunate %API 55–65 65–75 75–85 85–115 115–125 > 125 Total
55–65 <0.1 0 0.6 <0.1 0.2 0 1.0
65–75 0 0.6 0 0.4 0 0 1.0
75–85 0 0 0 0.9 0.6 0 1.5
85–115 0 0 0.3 80.8 3.7 < 0.1 84.9
115–125 0 0.2 0 3.4 7.5 0 11.2
> 125 0 0 0 0 0.6 0 0.6
Total < 0.1 0.8 0.9 85.5 12.6 < 0.1 100
(e) Dihydroartemisinin–piperaquine (N = 294)
Piperaquine
Dihydroartemisinin %API 55–65 65–75 75–85 85–115 115–125 > 125 Total
55–65 0 0 0 0 0 0 0.0
65–75 0 0 0 0 0 0 0.0
75–85 0 0 0.2 4.1 0 0 4.2
85–115 0 0 11.6 78.9 4.7 0.1 95.3
115–125 0 0 0 0.4 0 0 0.4
> 125 0 0 0 0 0 0 0.0
Total 0.0 0.0 11.8 83.4 4.7 0.1 100

ACT = artemisinin-based combination therapy; Alu = artemether–lumefantrine; API = active pharmaceutical ingredient.

The percentage of samples containing acceptable quantities of API for both the artemisinin component and partner drug is shown in bold.