Table 2. Pathways enriched with DEGs in MT vs. MC and AT vs. AC comparison groups.
| Pathway ID | Pathway description | Dif1 | Ref2 | P-value |
|---|---|---|---|---|
| MT vs. MC | ||||
| ko04142 | Lysosome | 20 | 948 | 3.10E-06 |
| ko04612 | Antigen processing and presentation | 12 | 389 | 8.18E-06 |
| ko03013 | RNA transport | 15 | 927 | 0.0009172 |
| ko03050 | Proteasome | 5 | 187 | 0.0069723 |
| ko00330 | Arginine and proline metabolism | 5 | 229 | 0.0157006 |
| ko00340 | Histidine metabolism | 3 | 98 | 0.0246248 |
| ko00620 | Pyruvate metabolism | 5 | 281 | 0.0339742 |
| ko00561 | Glycerolipid metabolism | 5 | 312 | 0.0493495 |
| AT vs. AC | ||||
| ko00190 | Oxidative phosphorylation | 38 | 399 | 2.48E-21 |
| ko03010 | Ribosome | 28 | 478 | 7.26E-11 |
| ko01100 | Metabolic pathways | 131 | 6447 | 1.15E-07 |
| ko03050 | Proteasome | 14 | 187 | 2.28E-07 |
| ko01120 | Microbial metabolism in diverse environments | 38 | 1604 | 0.00042 |
| ko03060 | Protein export | 6 | 118 | 0.004905 |
| ko00980 | Metabolism of xenobiotics by cytochrome P450 | 15 | 531 | 0.005158 |
| ko00062 | Fatty acid elongation in mitochondria | 4 | 54 | 0.005656 |
| ko00982 | Drug metabolism - cytochrome P450 | 15 | 537 | 0.005701 |
| ko00240 | Pyrimidine metabolism | 17 | 647 | 0.006134 |
| ko00280 | Valine, leucine and isoleucine degradation | 9 | 274 | 0.011196 |
| ko00020 | Citrate cycle (TCA cycle) | 8 | 229 | 0.011624 |
| ko04141 | Protein processing in endoplasmic reticulum | 22 | 990 | 0.013199 |
| ko04612 | Antigen processing and presentation | 11 | 389 | 0.015233 |
| ko00010 | Glycolysis / Gluconeogenesis | 8 | 241 | 0.015387 |
| ko00480 | Glutathione metabolism | 9 | 305 | 0.020979 |
| ko05130 | Pathogenic Escherichia coli infection | 9 | 305 | 0.020979 |
| ko03020 | RNA polymerase | 8 | 265 | 0.025434 |
| ko00640 | Propanoate metabolism | 6 | 185 | 0.036956 |
| ko00030 | Pentose phosphate pathway | 6 | 187 | 0.038618 |
| ko00350 | Tyrosine metabolism | 8 | 292 | 0.041385 |
| ko00450 | Selenocompound metabolism | 5 | 143 | 0.041797 |
| ko04621 | NOD-like receptor signaling pathway | 5 | 145 | 0.043921 |
| ko05100 | Bacterial invasion of epithelial cells | 9 | 357 | 0.049153 |
1The number of DEGs in a pathway.
2The total number of genes in a pathway.