Table 3. Pathologic features.
| Mean (range) | |
|---|---|
| Light microscopy | |
| Total glomeruli | 15 (2–43) |
| Sclerotic glomeruli | 2 (0–16), 11% (0–87%) |
| n (%) | |
| Glomerular pattern | |
| Crescentic | 26 (53) |
| Focal | 10 (20) |
| Diffuse | 16 (33) |
| Necrotizing foci | 20 of 26 (77) |
| Proliferative | 18 (37) |
| Focal | 2 (4) |
| Diffuse | 16 (33) |
| Mesangial proliferative | 5 (10) |
| Immunofluorescence microscopy | |
| Staining pattern | |
| Negative | 3 (6) |
| Mesangial alone | 20 (41) |
| Capillary wall alone | 2 (4) |
| Capillary wall and mesangial | 24 (49) |
| Immunoreactant | IgG | IgM | IgA | C3 |
|---|---|---|---|---|
| n (%) | 13 (27%) | 18 (37) | 14 (29) | 46 (94) |
| C3 only or C3+ single Ig | C3+IgG | C3+IgM | C3+IgA | C3 Only |
| n (%) | 2 (4%) | 8 (16%) | 3 (6%) | 18 (37) |
| Combined Igs | IgG IgM | IgG IgA | IgM IgA | IgG IgM IgA |
| n (%) | 3 (6%) | 6 (12%) | 3 (6%) | 2 (4) |
| Negative for all | Negative | |||
| n (%) | 3 (6) | |||
| n (%) | ||||
| Electron microscopy | ||||
| Mesangial deposits | 41 (84) | |||
| Subendothelial deposits | 22 (45) | |||
| Subepithelial deposits | 17 (35) | |||
| Subepithelial ‘humps' | 7 (14) | |||
| No deposits | 5 (10) | |||
Abbreviations: C3, complement component 3; Ig, immunoglobulin.