Table 3.
Association of BP with cardiovascular events
| BP (mmHg) | Unadjusted Hazard Ratio (95% CI) | Model 1 Hazard Ratio (95% CI) | Model 2 Hazard Ratio (95% CI) |
|---|---|---|---|
| Systolic BP | |||
| Q1 (≤128) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Q2 (>128–≤141) | 1.08 (0.73 to 1.60) | 1.08 (0.72 to 1.60) | 1.03 (0.69 to 1.54) |
| Q3 (>141–≤157) | 0.86 (0.57 to 1.30) | 0.84 (0.55 to 1.27) | 0.82 (0.54 to 1.24) |
| Q4 (>157) | 1.57 (1.09 to 2.27) | 1.51 (1.01 to 2.18) | 1.35 (0.92 to 1.97) |
| Diastolic BP | |||
| Q1 (≤64) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Q2 (>64–≤72) | 0.71 (0.48 to 1.03) | 0.69 (0.47 to 1.01) | 0.73 (0.50 to 1.07) |
| Q3 (>72–≤80) | 0.73 (0.50 to 1.07) | 0.73 (0.49 to 1.07) | 0.79 (0.53 to 1.18) |
| Q4 (>80) | 0.91 (0.64 to 1.30) | 0.93 (0.64 to 1.36) | 1.03 (0.70 to 1.52) |
| Pulse pressure | |||
| Q1 (≤57) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Q2 (>57–≤70) | 1.49 (0.99 to 2.23) | 1.44 (0.95 to 2.16) | 1.28 (0.85 to 1.93) |
| Q3 (>70–≤83) | 1.28 (0.82 to 2.00) | 1.26 (0.81 to 1.98) | 1.16 (0.74 to 1.81) |
| Q4 (>83) | 2.16 (1.45 to 3.21) | 2.03 (1.35 to 3.04) | 1.67 (1.10 to 2.52) |
Model 1: adjusted for age, sex, and race. Model 2: adjusted for covariates in model 1 plus smoking status, body mass index, history of hypertension, diabetes and cardiovascular disease, eGFR, serum hemoglobin, serum albumin, and Homocysteine in Kidney and ESRD randomized assignment. Q, quartile; 95% CI, 95% confidence interval.