Table 5.
Association of BP with composite outcome of progression to long-term dialysis or death
| BP (mm Hg) | Model 1 Hazard Ratio (95% CI) | Model 2 Hazard Ratio (95% CI) |
|---|---|---|
| Systolic BP | ||
| Q1 (≤128) | 1.00 (reference) | 1.00 (reference) |
| Q2 (>128–≤141) | 1.04 (0.86 to 1.27) | 0.98 (0.80 to 1.20) |
| Q3 (>141–≤157) | 1.26 (1.04 to 1.53) | 1.15 (0.95 to 1.40) |
| Q4 (>157) | 1.40 (1.15 to 1.69) | 1.19 (0.97 to 1.44) |
| Diastolic BP | ||
| Q1 (≤64) | 1.00 (reference) | 1.00 (reference) |
| Q2 (>64–≤72) | 0.95 (0.79 to 1.16) | 1.00 (0.82 to 1.21) |
| Q3 (>72–≤80) | 1.08 (0.89 to 1.31) | 1.16 (0.95 to 1.41) |
| Q4 (>80) | 1.10 (0.90 to 1.34) | 1.24 (1.01 to 1.52) |
| Pulse pressure | ||
| Q1 (≤57) | 1.00 (reference) | 1.00 (reference) |
| Q2 (>57–≤70) | 1.16 (0.95 to 1.40) | 0.98 (0.80 to 1.18) |
| Q3 (>70–≤83) | 1.29 (1.05 to 1.58) | 1.09 (0.89 to 1.33) |
| Q4 (>83) | 1.36 (1.11 to 1.66) | 1.03 (0.84 to 1.27) |
Model 1: adjusted for age, sex, and race. Model 2: adjusted for covariates in model 1 plus smoking status, body mass index, history of hypertension, diabetes and cardiovascular disease, eGFR, serum hemoglobin, serum albumin, and Homocysteine in Kidney and ESRD randomized assignment. Q, quartile; 95% CI, 95% confidence interval.