Spring (recruitment ended 2014)

Trial name or title	Evaluation of DHAP with and without single dose primaquine: an open-label randomized, controlled trial in anlong Veng, Cambodia
Methods	Randomized, open-label clinical trial to evaluate the safety and therapeutic efficacy of DP, and transmission blocking potential in combination with single dose primaquine (PQ) in northern Cambodia.
Participants	Up to 150 volunteers, including those with mild-moderate G6PD deficiency with uncomplicated P. falciparum or mixed malaria infections
Interventions	Consecutive daily oral doses of 120/960 mg of DP with or without a single 45 mg dose of PQ
Outcomes	Mosquito membrane-feeding assay Serial electrocardiograms and time-matched drug levels
Starting date	Not known - trial registration not yet located.
Contact information	M Spring
Notes	Identifed from preliminary results in 63rd Annual Meeting of the American Society of Tropical Medicine and Hygiene, ASTMH 2013 New Orleans