Skip to main content
. 2014 Sep 11;2014(9):CD010678. doi: 10.1002/14651858.CD010678.pub2

Table 7.

Optimal information size calculations; continuous outcomes

Outcome Type of test Mean in control group3 Mean in Intervention group4 SD of outcome Total sample size1,2
Coma resolution time Superiority 25 19 20 350
Equivalence 25 19 to 31 20 382
Parasite clearance time Superiority 42 36 20 350
Equivalence 42 36 to 48 20 382
Fever clearance time Superiority 48 42 20 350
Equivalence 48 36 to 54 20 382

1 These calculations were performed using a power calculator available at: http://www.sealedenvelope.com/power/ 2 All calculation were performed for a power of 80% and an α error of 0.05. 3 The mean in the control group is taken from the median control group across studies. 4 A six‐hour time difference was chosen to represent a clinically important benefit.