Table 10.
Additional data: Artemether versus quinine in adults
| Pre‐specified outcome | Trial reported outcome | Trial | No. of participants | Artemether | Quinine | Comparative results reported in article |
| Coma resolution time (h) | Median (IQR) | Hien 1996 VNM | 560 | 66 (30 to 132) | 48 (20 to 84) | P = 0.003 |
| Median (Range) | Karbwang 1995 THA | 97 | 48 (6 to 144) | 48 (6 to 144) | Not significantly different | |
| Fever clearance (h) | Median (IQR) | Hien 1996 VNM | 560 | 127 (60 to 216) | 90 (54 to 144) | < 0.001 |
| Median (Range) | Seaton 1998 PNG | 33 | 32 (20 to 112) | 48 (28 to 88) | P = 0.034 | |
| Median (Range) | Karbwang 1995 THA | 97 | 79 (16 to 147) | 84 (36 to 144) | Not significantly different | |
| Parasite clearance (h) | Median (IQR) | Hien 1996 VNM | 560 | 72 (54 to 102) | 90 (66 to 108) | < 0.001 |
| Median (range) | Seaton 1998 PNG | 33 | 48(4 to 72) | 52 (12 to112) | P = 0.381 | |
| Median (Range) | Karbwang 1995 THA | 97 | 54 (30 to 164) | 78 (18 to 168) | P = 0.007 |
IQR = interquartile range.