1. Sources of heterogeneity for urine reagent strip for microhaematuria.
Group | Co‐variate | Subgroup | n (N = 74) | Sensitivity (95% CI) | Specificity (95% CI) |
Overall | 0.75 (0.71‐0.79) | 0.87 (0.84‐0.90) | |||
Subgroup analysis | Reference standard | Higher quality (> 1 sample) | 10 | 0.71 (0.62‐0.80) | 0.85 (0.78‐0.93) |
Lower quality (1 sample) | 64 | 0.76 (0.71‐0.80) | 0.87 (0.84‐0.90) | ||
Threshold | ≥ +1 | 23 | 0.80 (0.73‐0.85) | 0.85 (0.78‐0.92) | |
Age | Children | 34 | 0.77 (0.71‐0.82) | 0.91 (0.87‐0.93) | |
Intensity of infection | Light | 28 | 0.73 (0.66‐0.79) | 0.88 (0.84‐0.92) | |
Sensitivity analysis | Concentration | Filtration only | 62 | 0.73 (0.69‐0.78) | 0.86 (0.82‐0.89) |
QUADAS Patient Selection | Low risk of bias | 16 | 0.77 (0.70‐0.86) | 0.86 (0.79‐0.92) | |
QUADAS Reference Standard | Low risk of biasa | 1 | ‐ | ‐ | |
QUADAS Flow and Timing | Low risk of bias | 43 | 0.77 (0.72‐0.82) | 0.87 (0.83‐0.90) |
aInsufficient data for synthesis.