Kitange 1993.

Study characteristics
Patient sampling	Cohort design; unclear sampling
Patient characteristics and setting	Species: S. haematobium Country: Tanzania Sample size: 253 Age range: not reported Participants: children in classes 1 to 7 in Melela primary school Setting: field study Praziquantel status before study: not reported
Index tests	RS‐Microhaematuria (BM Test 5L, Boehringer, Mannheim, Germany)
Target condition and reference standard(s)	S. haematobium infection measured by urine microscopy (centrifugation method)
Flow and timing
Comparative
Notes
Methodological quality
Item	Authors' judgement	Risk of bias	Applicability concerns
DOMAIN 1: Patient Selection
Was a consecutive or random sample of patients enrolled?	Unclear
Was a case‐control design avoided?	Yes
Did the study avoid inappropriate exclusions?	Unclear
		Unclear	Low
DOMAIN 2: Index Test RS‐Microhaematuria
Were the index test results interpreted without knowledge of the results of the reference standard?	Unclear
If a threshold was used, was it pre‐specified?	No
Was quality control done?	Unclear
		Unclear	Low
DOMAIN 2: Index Test RS‐Proteinuria
Were the index test results interpreted without knowledge of the results of the reference standard?	Unclear
If a threshold was used, was it pre‐specified?	No
Was quality control done?	Unclear
		Unclear	Low
DOMAIN 3: Reference Standard
Is the reference standards likely to correctly classify the target condition?	No
Were the reference standard results interpreted without knowledge of the results of the index tests?	Yes
Was quality control done?	Unclear
		High	Low
DOMAIN 4: Flow and Timing
Was there an appropriate interval between index test and reference standard?	Unclear
Did all patients receive the same reference standard?	Unclear
Were all patients included in the analysis?	Unclear
		Unclear