TABLE 4.
Antimicrobial susceptibility profiles of E. coli strains
| Drug | MIC (μg/ml)a for: |
|||
|---|---|---|---|---|
| W3110(pBBR5) | W3110(pBBR5.npp) | W3110 ΔyejABEF(pBBR5) | W3110 ΔyejABEF(pBBR5.npp) | |
| Peptidyl nucleoside antibiotics | ||||
| Pacidamycin D | >500 | 250 | >500 | 125 |
| Blasticidin S | 15.6 | 15.6 | 15.6 | 15.6 |
| Albomycin | NDb | ND | 250 | 15.6 |
| AMPs | ||||
| LL37 | >500 | >500 | >500 | >500 |
| Protamine | >500 | >500 | >500 | >500 |
| Cyclic polypeptides | ||||
| Colistin | <3.9 | <3.9 | <3.9 | <3.9 |
| Bacitracin | >2,500 | >2,500 | >2,500 | >2,500 |
| Glycopeptide: vancomycin | 312 | 312 | 312 | 312 |
| Heavy metals | ||||
| Nickel chloride | 1,250 | 625 | 1,250 | 625 |
| Copper sulfate | 1,250 | 1,250 | 1,250 | 1,250 |
| Cadmium acetate | 31.2 | 31.2 | 31.2 | 31.2 |
a
MICs were determined by 2-fold dilution assay in three or more independent experiments with similar results. Boldface values are more than 2-fold higher or lower MICs.
b
ND, not determined.