TABLE 2.
Distribution and predicted products of the secondary metabolite biosynthetic clusters within the P. temperata NC19 genome
| Gene cluster | Approximate location | Typea | Cluster presence in other Photorhabdus or Xenorhabdus genomesb | Predicted structurec |
|---|---|---|---|---|
| PT01 | pte_00186-pte_00208 | NRPS | plu3906-plu3935, pau_03747-pau_03784 | PT01 |
| PT02 | pte_00292-pte_00298 | Butyrolactone | pau_03747-pau_03784, pau_03338-pau_03397 | |
| PT03 | pte_00508-pte_00526 | Type I PKS | pau_01186-pau_01226, plu3516–3550 | |
| PT04 | pte_00783-pte_00787 | NRPS | plu3105-plu3144, pau_01452-pau_01511, XBJ1_1106-XBJ1_1149 | PT04 |
| PT05 | pte_00840-pte_00877 | NRPS | plu3105-plu3144, pau_01452-pau_01511 | PT05 |
| PT06 | pte_01018-pte_01031 | NRPS | Unique | PT06 |
| PT07 | pte_01583-pte_01602 | Type II PKS | plu4179–4210 | |
| PT08 | pte_02299-pte_02346 | NRPS | plu0164-plu0208 | PT08 |
| PT09 | pte_02429-pte_02439 | Bacteriocin | Unique | |
| PT10 | pte_02479-pte_02493 | Terpene | plu4322-plu4359 | |
| PT11 | pte_02783-pte_02807 | Type III PKS | pau_02342-pau_02390, plu2164-plu2205, XNC1_2270-XNC1_2323 | |
| PT12 | pte_03084-pte_03100 | NRPS-type I PKS | XBJ1_2661-XBJ1_2722 | PT12 |
| PT13 | pte_03528-pte_03541 | NRPS | XNC1_1677-XNC1_1733, XBJ1_2662-XBJ1_2722 | PT13 |
| PT14 | pte_03726-pte_03757 | NRPS | pau_01786-pau_01824, plu2716-plu2754 | |
| PT15 | pte_04021-pte_04055 | NRPS | plu0874-plu0915 | PT15 |
| PT16 | pte_04169-pte_04189 | Bacteriocin-NRPS | PT16 | |
| PT17 | pte_04198-pte_04227 | HglDE-like | pau_00901-pau_00936 | |
| PT18 | pte_04484-pte_04523 | NRPS | plu2642-plu2670 | PT18 |
a
NRPS, nonribosomal peptide synthetase; PKS, polyketide synthase.
b
Location within the other Photorhabdus and Xenorhabdus genomes based on locus tag. Plu and Pau numbers are P. luminescens TT01 and P. asymbiotica locus tags, while XBJ1 and XNC1 represent Xenorhabdus bovienii and X. nematophila.
c
Numbers correspond to predicted structures shown in Fig. S3 in the supplemental material.