Table 2.
Sodium arsenite | Sodium arsenate | |||||||
---|---|---|---|---|---|---|---|---|
Arsenic dose | Arsenic dose | |||||||
Tissue | Control | 50 ppm | 100 ppm | 150 ppm | Control | 100 ppm | 150 ppm | 200 ppm |
Blood (μg/ml) | 11.24 ± 2.35a | 304.99 ± 15.43b | 300.85 ± 18.89b | 257.62 ± 12.61c | 23.60 ± 2.99a | 228.44 ± 31.07b | 267.10 ± 13.79c | 273.23 ± 14.33c |
Liver (μg/g wet weight) | 1.73 ± 0.07a | 19.92 ± 2.16b | 14.85 ± 1.07c | 22.44 ± 3.02b | 3.54 ± 0.26a | 10.03 ± 0.58b | 19.32 ± 3.93c | 14.19 ± 0.96d |
Kidney (μg/g wet weight) | 2.06 ± 0.16a | 5.56 ± 0.28b | 39.54 ± 1.95c | 27.36 ± 2.03d | 2.06 ± 0.16a | 6.31 ± 0.37b | 32.84 ± 3.09c | 47.90 ± 2.99d |
Brain (μg/g wet weight) | 0.69 ± 0.05a | 3.11 ± 0.24b | 24.88 ± 2.57c | 35.21 ± 4.33d | 1.74 ± 0.15a | 18.95 ± 1.81b | 31.65 ± 2.15c | 22.11 ± 2.10d |
Heart (μg/g wet weight) | 0.20 ± 0.03a | 16.54 ± 1.11b | 53.54 ± 5.57c | 46.01 ± 2.30c | 0.02 ± 0.03a | 42.16 ± 2.39c | 18.80 ± 3.46b | 27.98 ± 2.99b |
Lung (μg/g wet weight) | 0.71 ± 0.03a | 4.97 ± 0.45a | 28.73 ± 3.73b | 33.20 ± 4.67b | 0.75 ± 0.02a | 6.64 ± 0.88a | 44.80 ± 7.18b | 28.39 ± 4.62b |
Spleen (μg/g wet weight) | 3.37 ± 0.29a | 40.35 ± 2.92b | 38.08 ± 1.60b | 58.32 ± 5.08c | 5.88 ± 0.33a | 20.66 ± 2.14b | 31.41 ± 3.40b | 23.12 ± 1.06b |
Each value represents the mean ± S.E.M. of 7 rats. Values within a row with different alphabets for each arsenic compound are significantly different at p < 0.05