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CYP1B1 deficiency attenuated mice body weight gain and adiposity induced by high fat diet feeding (n = 6-7). A. Mice body weight; B. Body weight gain, white adipose tissue and liver weight; C. Food consumption; D. Glucose tolerance test (GTT); E. H&E of Epididymal fat pad; F. Adipose size; G. Liver Oil-Red-O; H. Liver TG content. WT: wild type mice; KO: CYP1B1 deficient mice; W: week; BWG: body weight gain; WAT: white adipose tissue; TG: Triglyceride.
