Table 1.
Serial no. | Metric | Result | Remarks |
---|---|---|---|
1 | Measures of glycemic exposure | ||
1.1 | Mathematical mean BSL | 179.3 mg/dl (no. of BSLs used for calculations = 676) | Within recommended acceptable BSL range for hospitalized patients (140-180 mg/dl) |
1.2 | Mean BSL (not including hypoglycemic values) | 179.78 mg/dl (no. of BSLs used for calculation = 669) | Mean BSL ranged from 119 to 227 mg/dl in the RALS study4 |
1.3 | Median BSL | 188 mg/dl | |
2 | Efficacy of control (percentage of glucose readings within a specified range) | ||
2.1 | Values < 70 mg/dl | 1.03% | 3.11% in the RALS study4 |
2.2 | Values > 300 mg/dl | 4.88% | |
2.3 | Values within 80-139 mg/dl | 23.22% | |
2.4 | Values within 140- 180 mg/dl | 21.44% | |
2.5 | Values within 80-200 mg/dl | 52.8% | |
3 | Units of analysis | ||
3.(a) | Patient | ||
3.(a).1 | % of patients with hypoglycemia | 15.36% | |
3.(a).2 | % of patients with extreme hyperglycemia | 50% | |
3.(b) | Patient-stay | ||
3.(b).1 | Average glucose per patient-stay | 173.29 mg/dl | Most practical metric ofhyperglycemia associated risk |
3.(b).2 | % of patient-stays with average BSL within target range (140-180 mg/dl) | 50% | |
3.(b).3 | % of patient-stays with any BSL < 70 mg/dl | 15.38% | |
3.(b).4 | % of patient-stays with any BSL >300 mg/dl | 30.77% | |
3.(b).5 | Average number of glucose readings per patient for entire hospitalization (patient-stay) | 26 | 4.2 to 7.9 in a study3 |
3.(c) | Patient-day | ||
3.(c).1 | Average glucose per patient-day, ie, patient-day weighted mean BSL | 175.42 mg/dl | |
3.(c).2 | % of patient-days with average BSL within the target range (140-180 mg/dl) | 37.19% | |
3.(c).3 | % of patient-days with any BSL<70 mg/dl | 4.26% | |
3.(c).4 | % of patient-days with any BSL > 300 mg/dl | 14.63% | |
3.(c).5 | Average number of glucose readings per patient-day | 4.12 | 0.67 to 1.5 in a study3 |
4 | Patterns of insulin use | ||
4.1 | Regular human insulin was used in all patients | ||
4.2 | Sliding scale insulin was used for treatment of 22 patients (84.6%) | ||
4.3 | Insulin infusion was used in 4 patients (15.38) and for 14 patient-days (8.53%) | ||
4.4 | After starting insulin infusion it took an average of 4.4 hours for BSL to reach target range (140-180 mg/dl) |
Total number of blood glucose levels (BSLs) included for calculation = 676; total number of included patients = 26; total number of included patient-days = 164.