Table 3.
Association of Patient Characteristics With Insulin Initiation in Sulfonylurea Users: Multivariate Cox Regression Analyses (Backward Selection).
| Variable | Hazard ratio | 95% CI | P value |
|---|---|---|---|
| Age (56-80 years)a | 0.76 | 0.48-1.21 | .2406 |
| Age (>80 years)a | 0.98 | 0.55-1.74 | .9442 |
| Male sex | 1.02 | 0.74-1.41 | .8973 |
| eGFR (60-<90)b | 0.62 | 0.39-0.99 | .0464 |
| eGFR (30-<60)b | 0.79 | 0.45-1.36 | .3883 |
| eGFR (15-<30)b | 0.45 | 0.16-1.30 | .1410 |
| eGFR (baseline) | 0.99 | 0.98-1.01 | .5146 |
| Heart insufficiency | 1.52 | 1.07-2.16 | .0198 |
| Hypertension | 0.89 | 0.58-1.38 | .6126 |
| Diuretics | 2.27 | 1.49-3.46 | .0001 |
a
Reference: age ≤ 60 years.
b
Reference: eGFR ≥ 90 ml/min/1.73 m2.